By using common cobalt(II) complex as catalyst and oxygen as oxidant, styrene could be oxidized to styrene oxide and benzaldehyde under mild conditions. The impacts of reaction parameters including catalyst amount, initial volume ratio of solvent and temperature on styrene conversion and selectivity of products were evaluated to find a way for the regulation of oxidation products of styrene. The relationship of product yield and some main parameters could be established, which help to provide the target product as more as possible. Kinetic and thermodynamic calculation were also studied for a better understanding of reaction process. Beside the reaction system, the choice of reactors is another important aspect for the regulation of the product. Airlift loop reactor and bubble column reactor were compared for the styrene oxidation reaction. (C) 2017 Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved.