Unique hierarchical mesoporous layered-cube Mn2O3 has been synthesized in dual-solvent by a solvothermal method. The structure and morphology of the as-prepared materials were analyzed by Xray diffraction and electron microscope. The results show that the as-prepared sample can be indexed as rarely reported orthorhombic Mn2O3 with layered-cube morphology, and the possible formation mechanism is speculated. When evaluated as anode materials, the layered-cube Mn2O3 shows good electrochemical properties with high discharge capacity of 1664.7 mAh g(-1) at 1 A g(-1), maintains capacity of 906.8 mAh g(-1) after 100 cycles. Especially, sample maintains original morphology even at high current density (I A g(-1)) after 100 cycles. The excellent cycle stability and superior rate performance are attributed to hierarchical mesoporous structure in conjunction with its unique layered -cube, which can offer more ions and electrons transporting channels from different directions, provide high interfacial lithium storage and prevent the collapse of structure. (C) 2017 Elsevier B.V. All rights reserved.