The Box-Behnken design (BBD) approach was used in this work for the optimization of electropolymerization of poly(3,4-ethylenedioxythiophene) (PEDOT) with graphene oxide (GO) to yield high peak current response. The concentration of GO, electropolymerization potential and deposition time were investigated by response surface methodology (RSM). The interaction between these factors was studied and modeled to identify the significant and most influential parameters. The statistical analysis showed that concentration of GO, electropolymerization potential and deposition time had significant effects on the peak current response. The model was able to predict the peak current response with <2% error. The optimized PEDOT/GO composite showed wrinkles paper-like sheet morphology with better peak current response compared to PEDOT and GO. The incorporation of GO into PEDOT was further verified by using Fourier transform infrared and Raman spectroscopy. (C) 2017 Elsevier B.V. All rights reserved.