We have examined applicability to an integrated coal gasification combined cycle with carbon capture and storage (IGCC-CCS) system for Ni/Mo/TiO2 catalyst (Ni/Mo/Ti), which is a sulfur-olerant water-gas shift (WGS) catalyst (sour shift catalyst), developed for the purpose of generation efficiency improvement for the IGCC-CCS system. First, we carried out a 1000-h continuous experiment for the H2O/CO ratio of 1.2 mol/mol and catalyst inlet temperature of 200 C. The CO conversion rate maintained the initial activity for 1000 h and the catalyst crystal form after the experiment was not changed. Next, we estimated the effect of generation efficiency improvement for the IGCC-CCS system with the generating-end output of 370 MW by application of Ni/Mo/Ti. We estimated the net thermal efficiency for the H2O/CO ratio of 1.2 mol/mol was improved +0.8% points in comparison with that for the ratio of 1.6 mol/mol and could become 40.0% (HHV).The application of Ni/Mo/Ti to the IGCC-CCS system was judged to have a good prospect for contributing to efficiency improvement. (C) 2016 Elsevier Ltd. All rights reserved.