Isolation of low concentrated constituents from side streams of biobased processes has recently received increased technical and economical attention. For energy efficient acid isolation reactive extraction is proposed in literature. The crucial step for efficient process application is the solvent regeneration. Alternatively to conventional reactive extraction, physical extraction with chemical conversion simplifies the technical demand. For continuous operation of heterogeneous catalyzed esterification with physical extraction the Taylor-Couette disc contactor has proven to be applicable.