Powder Technology, Vol.307, 56-62, 2017
Spray-drying of curcumin-loaded octenylsuccinated corn dextrin micelles stabilized with maltodextrin
Self-assembled micelles of octenylsuccinated corn dextrin (OSCD) could be used as a vehicle to disperse curcumin in water, but the resultant solution is inconvenient for storage and transportation. To overcome these shortcomings, curcumin-loaded OSCD micelles were spray-dried with or without maltodextrin (MD). The physico-chemical properties of dried micelles and the stability of their redissolved solutions against thermal, freeze-thaw and add treatments were investigated. Spray-dried micelles appeared like unaerated balls, and their density, fluidity and curcumin retention increased with the addition of MD. DSC and XRD revealed the amorphous form of curcumin in dried micelles. In terms of curcumin retention, redissolved micelles presented better stability against freeze-thaw and acid treatments than thermal treatment. More importantly, MD highly stabilized the redissolved micelles against freeze-thaw-, acid- and thermal-treatment under 50-70 degrees C. The present study paves the way for industrial applications of curcumin-loaded OSCD. (C) 2016 Elsevier B.V. All rights reserved.