Supercritical fluid extraction was used for obtaining Saw Palmetto extract and influence of parameters on extraction overall yield and extract composition were studied and compared with results from the literature. Catchpole et al. [1] developed supercritical fluid extraction at three different pressures (25, 28 and 30 MPa) and at two different temperatures (313 K and 323 K), in order to study extraction yield and the composition of the extract. In present work different operating conditions, i.e. pressure (30 MPa and 45 MPa), temperature (313 K and 333 K) and ethanol as co-solvent (10% wow) were chosen as operating parameters. Extraction kinetic curves were modelled using Brunner's equation showing perfect fitting. Compositions were analysed by Gas Chromatography (GC) and High Performance Liquid Chromatography (HPLC) which confirmed the presence of fatty acids and beta-sitosterol. Solubility of the extract in CO2 was determined and studied by using different models. These models proved to fit quite accurate to experimental results. (C) 2016 Elsevier B.V. All rights reserved.