Asymmetric membranes provide a low ionic resistance of the functional separation layer together with a high mechanical stability. However, the microstructure of the porous support in the membrane assembly affects the overall flux significantly. This effect was studied by applying the binary friction model (BFM) for the support together with a modified Wagner equation for the dense membrane using transport relevant parameters obtained from micro computed tomography data of a tape cast Ba0.5Sr0.5Co0.8Fe0.2O3-delta support. The influence of different pore diameters and thicknesses of the support were compared for different feed gases (oxygen and air) and flow configurations (3-end, 4-end, assembly orientation). The effect of the support at large pore diameters (> 35 mu m) for the 3-end mode transport process using oxygen as feed gas, was negligible. This was not the case for the 4-end mode irrespective of the feed gas, and for the 3-end mode using air as feed gas. This was attributed to the binary diffusion term in the BFM. Thin small pored supports yield the same flux as thick large-pored supports.considering a non-linear relationship between thickness and pore size. This can be used for the optimization of the support's microstructure with regards to mechanical strength and permeability.