Solubility of 2-isopropylimidazole in nine organic solvents including methanol, ethanol, n-propanol, isopropanol, acetone, acetonitrile, ethyl acetate, toluene, 2-butanone and liquid mixture of (methanol + ethyl acetate) were determined experimentally by using the isothermal saturation method over the temperature range from (278.15 to 313.15) K under atmosphere pressure (101.2 kPa). The solubility of 2-isopropylimidazole in the pure solvents increased with a rise of temperature. In general, the mole fraction solubility obeyed the following order from high to low in different pure solvents: methanol > ethanol > 2-butanone > n-propanol > acetone > isopropanol > ethyl acetate > acetonitrile > toluene. For the (methanol + ethyl acetate) mixture with given initial composition, the mole fraction solubility of 2-isopropylimidazole increase with increasing temperature and mass fraction of methanol. The obtained solubility of 2-isopropylimidazole in the pure solvents was correlated with the modified Apelblat equation and All equation; and in the binary solvent mixture, the Jouyban-Acree model, van't Hoff-Jouyban-Acree model and modified Apelblat-Jouyban-Acree model. The maximum values of root-mean-square deviation (RMSD) and relative average deviation (RAD) were 19.29 x 10(-3) and 1.07%, respectively. In addition, the standard dissolution enthalpy was calculated. (c) 2016 Elsevier Ltd.