Thiophene, benzothiophene, and dibenzothiophene were extracted from isooctane using water and aqueous solutions of hydrochloric acid, sulfuric acid, nitric acid, acetic acid, sodium hydroxide, ammonium hydroxide, and sodium chloride at different concentrations, as solvents or extractants. The sulfur compound in isooctane at a definite concentration comprises model fuel. It was observed that the extraction ability of water is enhanced by adding those solutes or reagents. The aim of this work is to establish water-based solutions as an economic extractant for desulfurization of model fuel containing thiophenic sulfur compounds, by choosing the appropriate concentration of those aqueous extractants and using them at the most suitable extractive condition. The best result was obtained from aqueous hydrochloric acid solution, whose maximum sulfur removal efficiency toward thiophene, benzothiophene, and dibenzothiophene was 50, 28.2, and 26.8%, respectively. The effect of operational parameters on extraction, such as solvent/model fuel volume ratio, temperature, stirring speed, extraction time, and extraction cycle, was explored. The extraction temperature of 50 degrees C and 2:1 solvent/model fuel volume ratio under stirring at 1000 rpm for 60 min were found to be the optimum operating conditions. Finally, liquid liquid equilibria of the ternary mixture (thiophene + isooctane + aqueous HCl) were obtained at 40, 50, 60, and 70 degrees C at atmospheric pressure, and the equilibrium data were correlated with Othmer-Tobias and Hand correlations.