The current article aims to study the influence of pH, temperature, and oxidant concentrations on the dissolution process of metals from liquid crystal display (LCD) boards in a Na2S2O8 environment. The dissolution rate of metals is enhanced by the decrease of pH and increase of temperature and Na2S2O8 concentration. Based on the obtained results, a reaction mechanism was proposed and the reaction rate parameters (pre-exponential factor and activation energy) were determined. Kinetic analysis of the leaching process was performed in accordance with a shrinking core model. The activation energy was found to be 29,924, 11,871, 22,434, and 38,401J/mol for Cu, Sn, Ni, and Pt, respectively, in a temperature range of 30 degrees C-75 degrees C, which was also an indication of the combined transport-chemical control. The experimental results were in good agreement with the simulated data and revealed that persulfate solutions are suitable reactants for metals leaching from LCD boards.