Studies on micro-packed beds were reviewed pointing out major contributions with their key findings. Negligible mass transfer resistance and temperature gradients in micro-packed beds enables access to intrinsic kinetic data. Small scales also provide safety for extreme conditions and production of hazardous materials. Hydrodynamic studies in micro-packed beds suggest that stronger capillary forces give rise to hydrodynamic differences between macro- and micro-packed beds. Also, studies reach consensus that deviations from plug flow are minimal. Mass transfer studies in micro-packed beds have been mostly coupled with kinetic studies and results are typically reported as overall mass transfer coefficients two orders of magnitude higher than those in macro-scale. Among the reviewed studies, mass transfer has been identified as the scarcest in coverage and therefore a complementary work was performed on liquid-solid mass transfer coefficients (k(Ls)) in micro-packed beds. Experiments were performed within the diffusion-limited regime and the correspondence of k(LS) values with macro-scale correlations was discussed. It was found that in single-phase liquid flow, micro-scale kLs is closely predicted by macro-scale correlations. Comparison between macro- and micro-scale showed that volumetric mass transfer coefficients are higher in the latter due to higher solid-liquid interactions in confined volumes and high surface-to-volume ratios. (C) 2016 Elsevier B.V. All rights reserved.