The exploration of high efficient eletrocatalysts for hydrogen evolution reaction (HER) is a challenge as well as an opportunity for future applications in renewable sustainable energy. In this paper, a two-dimensional laminate MoS2/TiO2 heterostructure, in which the MoS2 nanosheet is loaded with TiO2 nanoparticles, have been synthesized via a facile hydrothermal process. The as-prepared MoS2/TiO2 electrode demonstrates improved electrocatalytic performance compared to bare MoS2 or TiO2 electrodes. Subsequently, a series of characterization techniques including X-ray diffraction and Raman spectroscopy are carried out to confirm crystallization of MoS2/TiO2 hybridization. Additional morphological and microstructural tests verify a distinct MoS2 framework, indicating a relative stability of MoS2 nanosheet platform. Electrochemical measurements reveal the overpotential and Tafel slope of as-prepared MoS2/TiO2 electrode are -185 mV and 46 mV/dec, which are very close to that of Pt electrode. The HER improvement is proposed to be attributed to the increase conductivity which derives from the reactive MoS2 layer structure, as well as the synergic effect of MoS2/TiO2 heterostructure. We hope this work could provide a novel prototype for the efficient hybrid HER catalysts. (C) 2016 The Electrochemical Society. All rights reserved.