Journal of the American Chemical Society, Vol.138, No.39, 12779-12782, 2016
Branch-Selective Hydroarylation: Iodoarene-Olefin Cross-Coupling
A combination of cobalt and nickel catalytic cycles enables a highly branch-selective (Markovnikov) olefin hydroarylation. Radical cyclization and ring scission experiments are consistent with hydrogen atom transfer (HAT) generation of a carbon-centered radical that leads to engagement of a nickel cycle.