A systematic approach for optimal batch water network synthesis is presented in this work, where multiple wastewater regeneration modules with various candidate technologies are taken into account. The integration of different regeneration technologies could further increase water reuse opportunities in the batch plants, thereby significantly reducing freshwater consumption and wastewater generation. Specifically, the regeneration modules are divided into batch and semicontinuous operating modes, which have never been considered completely in previous studies. A modified state-space superstructure incorporating a water-using subsystem, a regeneration subsystem, and buffer tanks is adopted to capture all realistic potential configurations. Correspondingly, a mixed-integer nonlinear programming model embedded with the scheduling of regeneration subsystem and buffer tanks is formulated to minimize the total annualized cost. In addition, a rule based solution procedure is developed to reduce the computation complexity and two illustrative examples are presented to demonstrate the effectiveness of the proposed methodology.