The advancements in connectivity among the entities belonging to industrial supply chain have given rise to more complex, global supply chain networks. These networks are often constituted of entities that belong to multiple such networks. Interactions among the entities in such networks are also influenced by whether they belong to the same enterprise or different ones. This work takes into consideration the effect of such interactions. The entities belonging to different enterprises are assumed to interact through auctions. An agent based simulation model that incorporates such auctions is used to represent multienterprise supply chain networks. The dynamics of the supply chain affected by the auction mechanism are investigated. Also a derivative free optimization methodology is proposed to find the optimal warehouse capacities for the minimization of total cost. (C) 2016 American Institute of Chemical Engineers