In this article, we demonstrated an integrated process for the direct production of tri(cyclopentane) with cyclopentanone which can be obtained from lignocellulose. The reaction was carried out in a dual-bed continuous flow reactor. In the first bed, cyclopentanone was selectively converted to 2,5-dicyclopentylcyclopentanol over the Pd-MgAl-HT (hydrotalcite) catalyst. Under solvent-free and mild conditions (443 K, 0.1 MPa H-2), high carbon yield (81.2%) of 2,5-dicyclopentylcyclopentanol was achieved. Subsequently, the 2,5-dicyclopentylcyclopentanol was further hydrodeoxygenated to tri(cyclopentane) in the second bed. Among the investigated catalysts, the Ni-H beta-DP prepared by deposition-precipitation (DP) method exhibited the highest activity for the hydrodeoxygenation step. By using Pd-MgAl-HT as the first bed catalyst and Ni-HbDP as the second bed catalyst, tri(cyclopentane) was directly produced at high carbon yield (80.0%) with cyclopentanone as feedstock. This polycycloalkane has high density (0.91 kg/L) and can be used as additive to improve the density and volumetric heating value of bio-jet fuel. (C) 2016 American Institute of Chemical Engineers