A novel integrated precipitation reactor (PR) and membrane separator (MS) system was developed for the removal of radioactive I- from simulated liquid waste. The PR-MS system was evaluated at the lab-scale, the I- removal efficiency reached approximately 97.0% and the concentration factor (CF) value was 1050 when the concentration of added Na2SO3 was 40 mg/L and the CuCI dosage was 260 mg/L. The addition of Na2SO3 played an important role in the removal of dissolved oxygen (DO) and the formation of CuI. These reactions, including the oxidation of SO32-, the dissociation of CuCI, the disproportionation of Cu+, and the formation of CuI and Cu2O, occurred in the PR. Furthermore, the influence of the concentration of added CO32- on copper removal was investigated, and solid-liquid separation and copper removal were simultaneously attained in the MS. The I- removal efficiency gradually decreased from 97.0% to 58.5% and the Cu2(+) concentration in the effluent decreased from 18.71 mg/L to 0.719 mg/L with the addition of CO32- at a concentration that ranged from 0 to 80 mg/L. Experimental results show the PR-MS system is of great potential for industrial application on treatment of liquid waste contaminated with radioactive I-. (C) 2016 Elsevier B.V. All rights reserved.