A quick, selective and sensitive electrochemical sensor for nonenzymatic hydrogen peroxide (H2O2) detecting was fabricated. It was based on the in situ & controlled preparation of platinum nanoparticles (Pt) dopping into graphene sheets@cerium oxide (GS@CeO2) nanocomposites sensitized screen printed electrode (SPE). Different sizes of Pt were dopped into GS@CeO2 nanocomposites by using a simple electroless plating method. X-ray powder diffractometer (XRD) combines with Fourier transform infrared spectrum (FTIR) were used to characterize the composition of the hybrid nanomaterials. Electrochemical impedance spectroscopy (EIS) and Scanning electron microscopy (SEM) were employed to study the interfacial properties and morphologies of different electrodes. The electrochemical properties of electrochemical sensor were investigated by cyclic voltammetry (CV) and chronoamperometry (i-t curve) methods. After all experimental parameters were optimized, the GS@CeO2-Pt hybrid nanomaterials modified SPE (SPE I GS@CeO2-Pt) showed a good performance towards the electrocatalytic reduction of H2O2. A wide linear detection range (LDR) extends from 1.0 x 10(-3) mM to 10.0 mM (R = 0.9999) and a low limit of detection (LOD) of 0.43 x 10(-3) mM (S/N = 3) were achieved. The sensor was also simple, stable and reliable. It was applied to the determination of H2O2 in contact lens care solutions with good accuracy and recovery. (C) 2016 Elsevier B.V. All rights reserved.