Bio-fuels like alcohols, including butan-1-ol are produced from biomass by fermentation, and distillation. Ionic liquids (ILs) are novel attractive solvents, which can be used for removing butan-1-ol from the aqueous fermentation broth. In this work, the 1-dodecyl-3-methylimidazolium bis{(trifluoromethyl) sulfonyl} imide, [DoMIM][NTf2] is proposed as an extractive solvent. The temperature of fusion and the enthalpy of fusion, obtained with DSC, the density and viscosity of [DoMIM][NTf2] as a function of temperature have been measured over a temperature range (298.15-368.15) K. The limiting activity coefficients gamma(infinity)(13), for 65 solutes including alkanes, cycloalkanes, alkenes, alkynes, aromatic hydrocarbons, alcohols, water, thiophene, tetrahydrofuran, ethers, and ketones in the [DoMIM][NTf2] were determined by gas-liquid chromatography at six temperatures from 318.15 K to 368.15 K. The partial molar excess Gibbs energies Delta G(1)(E,infinity), enthalpies Delta H-1(E,infinity), and entropies Delta S-1(E,infinity) at infinite dilution were calculated from the experimental gamma(infinity)(13) values obtained over the temperature range. The gas-liquid partition coefficients, K-L were calculated for all solutes and the Abraham solvation parameter model was discussed. The selectivity and capacity for butan-1-ol/water separation problem were calculated from gamma(infinity)(13) and compared to literature values for bis {(trifluomethyl) sulfonyl} imide-based ILs with different cations and with all available data for ILs. (C) 2016 Elsevier Ltd.