Biocompatible and photoluminescent keratin/poly(vinyl alcohol)/carbon quantum dot nanofiber: A novel multipurpose electrospun mat

Chohye Lee; Bishweshwar Pant; Al-Mahmnur Alam; Taehee An; Hea-Jong Chung; Seong-Tshool Hong; Soo-Jin Park; Mira Park; Hak-Yong Kim

Macromolecular Research, Vol.24, No.10, 924-930, October, 2016

DOI10.1007/s13233-016-4124-3 Export Citation

Biocompatible and photoluminescent keratin/poly(vinyl alcohol)/carbon quantum dot nanofiber: A novel multipurpose electrospun mat

Chohye Lee¹, Bishweshwar Pant², Al-Mahmnur Alam¹, Taehee An¹, Hea-Jong Chung³, Seong-Tshool Hong³, Soo-Jin Park², Mira Park^{4, †}, and Hak-Yong Kim^{1, 4, †}

¹Department of BIN Convergence Technology, Chonbuk National University, Jeonju, Jeonbuk, Korea
²Department of Chemistry, Inha University, Gyeonggi, Korea
³Department of Biomedical Sciences, Chonbuk National University Medical School, Jeonju, Jeonbuk, Korea
⁴Department of Organic Materials & Fiber Engineering, Chonbuk National University, Jeonju, Jeonbuk, Korea

E-mail:,

Carbon quantum dots (C-dots) triggered photoluminescent keratin/poly(vinyl alcohol) (PVA)/C-dots nanofibers (NFs) with optical transparency and biocompatibility were prepared by an electrospinning process. The synthesized NFs were characterized by field-emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), ultraviolet-visible spectroscopy, and spectrofluorometer. C-dots are capable of emitting excitation dependent photoluminescence (PL) emission spectra at room temperature and are nontoxic at reasonably high concentrations. Optically transparent keratin/PVA/C-dots NFs were found to exhibit excitation dependent PL emission at the wavelengths of 488, 535, and 625 nm during excitation at the wavelengths of 360, 480, and 545 nm, respectively, similar to the C-dots. In vitro cytotoxicity tests against NIH-3T3 cell lines revealed a good biocompatible nature of keratin/PVA/C-dots. The results indicated that the fabricated composite NFs mat not only exhibited a well preserved quantum confinement effect of the C-dots along with its transparency but also showed biocompatibility in the living cell environment.

Keywords:electrospinning;carbon quantum dots;keratin;poly(vinyl alcohol);photoluminescence;biocompatibility

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[3] Yan R, Gargas D, Yang P, Nat. Photonics, 3, 569 (2009)

[4] Pant B, Barakat NAM, Pant HR, Park M, Saud PS, Kim JW, Kim HY, J. Colloid Interface Sci., 434, 159 (2014)

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[11] Tetsuka H, Nagoya A, Asahi R, J. Mater. Chem. C, 3, 3536 (2015)

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[17] Wang S, Li Y, Wang Y, Yang Q, Wei Y, Mater. Lett., 61, 4674 (2007)

[18] Wang P, Wang Y, Tong L, Light Sci. Appl., 2, e102 (2013)

[19] Di Benedetto F, Camposeo A, Persano L, Laera AM, Piscopiello E, Cingolani R, Tapfer L, Pisignano D, Nanoscale, 3, 4234 (2011)

[20] Mao XJ, Zheng HZ, Long YJ, Du J, Hao JY, Wang LL, Zhou DB, Spectroc. Acta Pt. A-Molec. Biomolec. Spectr., 75, 553 (2010)

[21] Jana J, Ganguly M, Das B, Dhara S, Negishi Y, Pal T, Talanta, 150, 253 (2016)

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[25] Choi J, Panthi G, Liu Y, Kim J, Chae SH, Lee C, Park M, Kim HY, Polymer, 58, 146 (2015)

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[27] Li JS, Li Y, Liu X, Zhang J, Zhang Y, J. Mater. Chem. B, 1, 432 (2013)

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