A chiral C-3-symmetric cubane cluster, [Cu4I4(TMP)(4)], with enough long Cu-Cu distances to eliminate the presence of Cu-Cu interaction has been synthesized and characterized, Which shows simultaneoris luminescent thermochromism, solvatochromism, Vapo-chromism, and mechanochromism and is a multiply stimuli-responsive chromic luminescent material. This complex could partly transform into a yellow-emissive bicapped cubane cluster, [Cu6I6(TMP)(4)(MeCN)(2)], in acetonitrile (MeCN) vapor and solution, which provides some insight into vapochromisim and solvatiochromism. This work challenges and Makes us reconsider the conventional viewpoint that: Cu-Cu interaction is involved in thermochromism and mechanochromism of copper complexes.