Dead-ended anode (DEA) mode is commonly applied in fuel cell vehicles for the hydrogen purge at the anode side, to reduce fuel waste and enhance fuel cell efficiency. Anode purge is necessary and is definitely important with respect to removing liquid water and accumulated nitrogen in the gas diffusion layer and the flow field of the DEA-mode fuel cell. In this paper, the effect of different purge strategies on the stack performance and system efficiency is investigated experimentally using fast data acquisition and advanced tools, such as the fast cell voltage measurement (CVM) system and the mass spectrum. From the fast data acquisition, the voltage stability, liquid water and nitrogen concentration measurement in the anode exhaust are compared and analyzed under different purge strategy designs and using different purge valves. The results show that under the optimal purge strategy, the DEA fuel cell stack can achieve the desired stability and system efficiency based on the analysis of the cell voltage and purge volume. Moreover, the diameter of the purge valve has a great impact on the voltage stability because a diameter change will result in a different pressure drop and purge volume when the purge valve is open. (C) 2016 Elsevier B.V. All rights reserved.