As the conventional centralized automatic generation control (AGC) is inadequate to handle the ever-increasing penetration of renewable energy and the requirement of plug-and-play of smart grid, this paper proposes a mixed homogeneous and heterogeneous multi-agent based wolf pack hunting (WPH) strategy to achieve a fast AGC power dispatch, optimal coordinated control, and electric power autonomy of an islanding smart distribution network (ISDN). A virtual consensus variable is employed to deal with the topology variation resulted from the excess of power limits and to achieve the plug-and-play of AGC. units. Then an integrated objective of frequency deviation and short-term economic dispatch is developed, such that all units can maintain an optimal operation in the presence of load disturbances. Four case studies are undertaken to an ISDN with various distributed generations and microgrids. Simulation results demonstrate that WPH has a greater robustness and a faster dynamic optimization than that of conventional approaches, which can increase the utilization rate of the renewable energy and effectively resolve the coordination and electric power autonomy of ISDN. (C) 2016 Published by Elsevier Ltd.