A commercial system that is comprised of a CE coupled to an ESI triple quadrupole mass spectrometer was equipped with two capacitively coupled contactless conductivity detectors (C(4)Ds). The first (CD)-D-4 was positioned inside the original cartridge, and the second (CD)-D-4 was positioned as close as possible to the ESI probe entrance by using a 3D-printed support. The C(4)Ds electropherograms werematched to the ESI-MS electropherogram by correcting their timescales by the factor L-T/L-D, where L-T and L-D are the total capillary length and the length until the (CD)-D-4, respectively. A general approach formethod development supporting the simultaneous conductivity and MS detection is discussed, while application examples are introduced. These examples include the use of (CD)-D-4 as a simple device that dismiss the use of an EOF marker, a low-selectivity detector that continuously provide information about unexpected features of the sample, and even a detector that can be more sensitive than ESI-MS. The (CD)-D-4 used in this setup proved to have a smaller contribution to the peak broadening than ESI-MS, which allowed that a (CD)-D-4, positioned at 12 cm from the inlet of an 80-cm-long capillary, could be used to foresee position and shape of the peaks being formed 6.8 times slower at the ESI-MS electropherogram.