Chemistry Letters, Vol.45, No.7, 798-800, 2016
Palladium-catalyzed Asymmetric Allylic Alkylation Using C-2-symmetric Chiral Bidentate Bis(N-heterocyclic carbene) Ligands with the o-Xylylene Framework
An asymmetric allylic alkylation reaction of 1,3-diphenyl-prop-2-en-1-y1 acetate with dimethyl malonate was examined using C-2-symmetric chiral bidentate bis(N-heterocyclic carbene)-based palladium catalysts. The alkylated product was obtained in 96% yield with good enantioselectivity (80% ee).