The photocatalytic degradation of s-triazine herbicides, viz. propazine (Pro), cyanazine (Cya) and terbuthylazine (Ter), by center dot OH radicals over TiO2 were investigated. The results indicate that all three her- bicides were degraded within 90 min, and the rate constants follow the order: Cya > Pro > Ter. The center dot OH radicals are heavily involved in the degradation process. It was observed that the adsorption and subsequent reaction of s-triazine herbicides with h(+). on the surface of catalyst are significantly subject to the steric-hindrance effect of side chains. Also, there is obvious promotion of degradation rate in the presence of electron-capture agent BrO3-. And with the addition of H2O2, there could be promotion as well as suppression of degradation rate across the herbicides. Finally, the point charges, frontier election densities and reaction energies were analyzed to characterize the adsorption orientation, reaction active sites and reaction direction of s-triazine. Based on the calculated data and experimental results, the general degradation pathways are proposed, such as cleavage of side chains, substitution of Cl atom by center dot OH, and hydroxylation as well as abstraction of hydrogen atoms. (C) 2016 Elsevier B.V. All rights reserved.