Journal of Chemical Thermodynamics, Vol.98, 135-139, 2016
The vapor pressure and vaporization enthalpy of R-(+)-menthofuran, a hepatotoxin metabolically derived from the abortifacient terpene, (R)-(+)-pulegone by correlation gas chromatography
The vapor pressure as a function of temperature and its vaporization enthalpy at T = 298.15 K of R-(+)-menthofuran, a substance metabolically derived from R-(+)-pulegone that is both a flavoring agent at low concentrations and a hepatotoxin at larger ones, is evaluated by correlation-gas chromatography. A vapor pressure p/Pa = (36 +/- 12) has been evaluated at T = 298.15 K, and a normal boiling temperature of T-b/K = 482.4 K is predicted. A boiling temperature of T-b/K = 374.3 compares with the literature value of T-b/K = 371.2 at reduced pressure, p/kPa = 2.93. The vaporization enthalpy of (56.5 +/- 3.0) kJ.mol(-1) compares to an estimated value of (57.8 +/- 2.9) kJ.mol(-1). (C) 2016 Elsevier Ltd. All rights reserved.