Spectral theory of turbulence has been applied to obtain expressions for the mass transfer coefficient in the case of Newtonian and non-Newtonian fluids. Expression of mass transfer coefficient obtained from the spectral theory of turbulence is then compared with that obtained from other hydrodynamic models. Similarities and advantages of these models are discussed. Mass transfer models developed on the basis of hydrodynamic consideration, show their potential in providing mechanistic aspect of transport behavior with respect to mixing and viscous stresses of the fluid on the membrane surface. The effects of flow index and consistency factor of the non-Newtonian fluids, on the mass transfer phenomena in a membrane tube are discussed.