An ex-situ tensile fatigue and creep based accelerated stress test (TFC-AST) is proposed to evaluate the mechanical stability of catalyst coated membranes (CCMs) used in fuel cells. The fatigue-creep action of the TFC test is analyzed by tensile and hygrothermal expansion measurements on partially degraded specimens supplemented by microstructural characterization using transmission electron microscopy, revealing significant decay in mechanical properties as well as morphological rearrangement due to the combined fatigue and creep loading. Through comparison with in-situ hygrothermally degraded CCMs, the TFC-AST protocol is demonstrated to be an economical alternative to the costly in-situ mechanical accelerated stress tests that can reduce the test duration by more than 99%. (C) 2016 Elsevier B.V. All rights reserved.