Effects of different operating conditions on the CO2 capture and mass transfer performance of the absorption of CO2 into a hybrid solvent MEA-Methanol were studied in a pilot-plant absorber packed with three different packing consist of Sulzer BX500, Mellapale Y500 and Pall rings 16 x 16. The results showed that the structured packing had an obvious advantage in the mass transfer performance. And Sulzer BX500 was better than Mellapale Y500 for it had a more uniform gas-liquid distribution on the packing surface. In addition, CO2 lean loading, lean solvent temperature, lean solvent flow rate and flue gas flow rate all had great effects on the absorption performance of the MEA-Methanol absorption system. (C) 2016 Elsevier B.V. All rights reserved.