Ceramic microchannel reactors offer significant advantages to current microchannel reactor technology. Ceramic micro-reactors are able to operate at high temperatures and harsh chemical environments through the use of relatively inexpensive materials and manufacturing processes. Coupled with self-sustained operation through autothermal reforming (ATR) or catalytic partial oxidation (CPOX) of methane, ceramic microchannel reactors can increase reforming efficiency and expand the capabilities of hydrogen and syngas production. This work aims to assess the performance of a novel ceramic micro channel reactor for a wide variety of methane reforming conditions and reactive flow rates. Additionally, a computational fluid dynamics (CFD) model implemented in ANSYS Rum. simulates fluid flow, heat transfer, and catalyzed heterogeneous chemistry in a three-dimensional model. Experimental testing demonstrates stable operation for both ATR and CPDX; no evidence of structural or catalyst degradation is observed in the presence of exothermic chemistry. Autothermal reforming in the novel ceramic microchannel reactor shows promising results, achieving similar to 90% methane conversion at a gas hourly space velocity (GHSV) of 75,000 h(-1). CFD model results accurately predict reactor outputs from experimental data and provide further insight into the internal reactor chemistry and reaction kinetics. Copyright (C) 2015, Hydrogen Energy Publications, LLC. Published by Elsevier Ltd. All rights reserved.