Graphene-based micromotors with an alveolate surface of MnO2 hydrogen peroxide propelled are described. The micromotors display powerful propulsion in a low fuel level (2.5%), with a speed of over 111 mu m s(-1), as well as efficient locomotion in biological media such as bovine serum. It has a good motion even in very low levels of the hydrogen peroxide fuel (down to 0.15%), which can compare favorably with Pt. The attractive properties of these new chemical-prepared micromotors hold great promise for biomedical applications.