Catalytic hydroprocessing of fatty acid methyl esters (FAME) is a promising route for enhancing the properties to cover their disadvantages to replace conventional motor fuel. Non-sulfided CoFe/gamma-Al2O3 catalyst was synthesized for the hydrotreatment of FAME derived from Jatropha oil. Straight-chain alkanes in the range C15-C18 were the major products. A maximum FAME conversion of 82.56% and diesel selectivity of 81.2% were obtained at 400 degrees C and 2 MPa. Effect of the reaction temperature and reaction time on the FAME conversion and diesel selectivity were studied. Fe incorporation facilitated the cobalt oxide reduction by H-2 spill over and cobalt oxide dispersion, which facilitate C-O bond activation and breaking.