To replace the conventional chemical bath deposition method, which is time-consuming and has a high impurity level, a chemical single-step deposition process employing a S/Sb ratio-controlled SbCl3-thiourea complex solution is introduced to load Sb2S3 into a mesoporous TiO2 electrode. This technique enables the fabrication of efficient and reproducible Sb2S3-sensitzed inorganic-organic heterojunction hybrid solar cells with hole-conducting conjugated polymers. The most efficient cell exhibits a short-circuit current density of 16.1 mA cm(-2), an open circuit voltage of 595.5 mV, and a fill factor of 66.5%, yielding a power conversion efficiency of approximate to 6.4% at standard AM1.5G condition (100 mW cm(-2)).