This research was to study the effect of blast furnace dust (BFD) as a new reactive material for the degradation of chlorinated organic (COCs) and endocrine disrupting compounds (EDCs). When 100 g/L of BFD was used, the effective degradation of tetrachloroethylene (PCE) was obtained. The cis-DCE (0.93 mM) was dechlorinated to below detection limit within 120 h of reaction. Among various COCs and EDCs, they were degraded at least 90% except for sodium perchlorate. The metabolites of 4-tert-octylphenol (4-t-OP) were identified as 2,4,4-trimethyl-2-pentanol, hydroquinone and 2-tert-octylhydroquinone, respectively. The effective degradation of PCE and 4-t-OP was occurred at range of pH 4-7. A total of 100% of cis-DCE and 86% of 4-t-OP were degraded in fed-batch experiments after 264 h. A solution of highly enriched bacteria completely insolubilized 2.14 mM of Zn eluted from BFD within 168 h of culture. These researches will provide more information related to the application for other contaminated water and wastewater treatments. (c) 2013 Elsevier Ltd. All rights reserved.