A series of star shaped photochromic bisthienylethene derivatives were synthesized by Still coupling reaction and fully characterized. Their photocromic properties were investigated in solution state. With the thiophene or thiazole "arms" attached to a photochromic core, the reversible ring-open and ring-close photoismerization reactions undergoes smoothly when irradiated with ultraviolet and visible light alternately. Molecular geometric structures were optimized and HOMOs/LUMOs were calculated by Dmol(3) package of Material Studio. Two key factors, the distance between reactive carbon atoms and the electron distribution in unoccupied orbitals (LUMO), favored the cyclization/cycloreversion triggered by photons.