Mesogens with a chalcone central linkage are rare. It is believed that the chalcone linkage is not conducive to mesomorphism. But when chalcone linkage is present with other central linkages like azomethine, ester or azo it becomes condusive to mesomorphism. In the present study two new homologous series viz. 1-(4'-butyloxybiphenyl-4-yl)-3-(4-alkoxyphenyl) prop-2-en-1-one (Series-I) and 4-[3-(4'-butoxybiphenyl-4-yl)-3-oxoprop-1-en-1-yl] phenyl 4-alkoxybenzoate (Series-II) were synthesized having the chalcone as a central linkage. Series-I having only chalcone central linkage through it exhibit mesomrphism due to the presence of alkoxy biphenyl group at one end which is rich source to provide to increase linearity and rigidity of the molecule. Series-II which contains chalcone as well as ester as a central linkage and it also exhibit mesomorphism. The compounds of the both series have been characterized by standard methods. Their liquid crystalline properties have been investigated by optical polarizing microscopy and DSC studies.