By generating microgroove pattern on the plastic substrate, liquid crystals (LCs) are aligned on the flexible substrates immediately without coating alignment polymer. This flexible LC cell proposed in this paper preserves comparable electro-optical properties while bending. The plastic film and the alignment layer integrated into an alignment substrate could prevent cracks of the additional polymer alignment layer during the bending condition. This method holds promises to be applicable to the roll-to-roll process to increase efficiency of the production.