Microcapsules of durability and deformability along with excellent transparency, which was designed for the application of electrophoretic display system, have been synthesized. Microcapsules were synthesized by two-step condensation polymerization using melamine-formaldehyde (MF) resin. In this work, durability and flexibility of MF microcapsules activated by acid catalyst were characterized by compression test accompanied by visual inspection. Microcapsules of MF-AA (using acetic acid as acid catalyst) were rapidly ruptured at force 0.8 mN, while those of MF-MA (using maleic anhydride as acid catalyst) were highly deformed to show a permanent failure at 3.8 mN. Furthermore MF-MA microcapsule showed extremely higher deformation ratio than MF-AA, implying that the maleic anhydride activated system would be much more durable and flexible than the MF system employing AA.