We have studied the influence of fine particles on the stability of a granular medium in a rotating drum. The stability diagram of this system was established as a function of the drum rotation speed, fine particle content and relative humidity. Four regimes were observed. At low fine content, an avalanching regime is encountered at low rotation rate, and a continuous flow regime at high rotation rate. At high fine content, a stick slip regime at the drum wall is seen at low rotation rate and a continuous sliding regime at high rotation rate. The influence of fines is ambivalent At low fine content, they fluidize the pile and decrease its stability, by granular lubrication. At high fine content, they solidify the pile and increase its stability, by jamming the grain assembly. The enhancement of humidity increases the stability for high fine content, but has no effect for low fine content. (C) 2015 Elsevier B.V. All rights reserved.