Particulate matter is one of the most significant pollutants in indoor environments. The study of vertical profile concentration coefficients of different particulates leads us to figure out the most accurate pattern of vertical profile change of these hazardous particles. In this case, three different sizes of particulate vertical profile patterns, PM1.0, PM2.5, and PM10, were evaluated in indoors in the city of Karaj. Samplings of first and fourth floors of 5 buildings located in different areas of Karaj were conducted constantly during 2011. The results of Mahestan Station illustrate the highest average concentration of PM10 (173 mu g/m(3)) whereas the RajaieShahr Station measurements indicates the highest average concentrations of PM2.5(66 mu g/m(3)) and also PM1.0(51 mu g/m(3)). Generally, the concentrations of the particulates in the first floors were higher than that in the fourth floors, and according to the air evaluation stations, all the particulates including PM1.0, PM2.5, and PM10 had concentrations higher than the annual standard.