Two new homologous series, each consisting of 12 mesogens with isoamyloxy and isobutoxy branching terminal groups, have been synthesized, and their mesomorphic properties are studied. All the derivatives are mesomorphic in nature, with the lower members exhibiting nematic mesophase and the higher derivatives showing smectic-c and nematic phase. The effect of branching on mesomorphism has been investigated by comparing them with structurally similar unbranched homologous series.