Precise characterization of wettability of CO2-brine-rock system and CO2-brine interfacial tension at reservoir conditions is essential as they influence capillary sealing efficiency of caprocks, which in turn, impacts the structural and residual trapping during CO2 geo-sequestration. In this context, we have experimentally measured advancing and receding contact angles for brine-CO2-mica system (surface roughness similar to 12 nm) at different pressures (0.1 MPa, 5 MPa, 7 MPa, 10 MPa, 15 MPa, 20 MPa), temperatures (308 K, 323 K, and 343 K), and salinities (0 wt%, 5 wt%, 10 wt%, 20 wt% and 30 wt% NaCl). For the same experimental matrix, CO2-brine interfacial tensions have also been measured using the pendant drop technique. The results indicate that both advancing and receding contact angles increase with pressure and salinity, but decrease with temperature. On the contrary, CO2-brine interfacial tension decrease with pressure and increase with temperature. At 20 MPa and 308 K, the advancing angle is measured to be 110, indicating CO2-wetting. The results have been compared with various published literature data and probable factors responsible for deviations have been highlighted. Finally we demonstrate the implications of measured data by evaluating CO2 storage heights under various operating conditions. We conclude that for a given storage depth, reservoirs with lower pressures and high temperatures can store larger volumes and thus exhibit better sealing efficiency. (C) 2015 Elsevier Inc. All rights reserved.