Continuous and stable operation of a membrane reactor for 1054 h to dehydrogenate methylcyclohexane for the purpose of producing high-purity H-2, using a dimethoxydiphenylsilane (DMDPS)-derived silica membrane, is successfully demonstrated. The silica membrane used was prepared via a chemical vapor deposition method; using DMDPS as a precursor, and Pt/Al2O3 catalysts were employed and loaded inside the tubular membrane. During the 1054 h of continuous operation, an equilibrium shift was stably demonstrated, because of the stable extraction of the produced H-2 from the reaction side to the permeate side, and, accordingly, the purity of H-2 in the permeate gas was stably high. Although the DMDPS-derived membrane showed a slight decrease in performance after 1054 h of operation, followed by regeneration under an H-2 atmosphere, this first successful demonstration of the long-term stable operation of a membrane reactor using Silica membranes is Of significance to its practical and industrial use.