The cubic-plus-association (CPA) equation of state (EoS) has already been proven to be a successful model for phase equilibrium calculations for systems containing associating components and has already been applied for asphaltene modeling by few researchers. In the present work, we apply the CPA EoS to determine asphaltene precipitation onset conditions for various reservoir fluids but with a different modeling approach than literature approaches. A simple oil characterization technique, based on SARA analysis, is adopted which divides the C6+ fraction of the oil into "heavy component" and asphaltene. Self-association between asphaltene molecules and cross-association between asphaltene and heavy component molecules are considered. Experimental data of several reservoir fluids are compared with model results and it is found that the temperature dependent cross-association energy correlates asphaltene phase envelope quite well in agreement with the experimental data. Two experimental asphaltene onset points at different temperatures and one bubble point data of reservoir fluid are required in order to determine the temperature dependent cross-association energy and critical pressure of heavy component respectively. The effect of gas injection on asphaltene precipitation is also correlated with experimental data by tuning a single binary interaction parameter of the injected gas component and asphaltene pair. (C) 2015 Elsevier B.V. All rights reserved.