Jatropha oil (JO) was transesterified with dimethyl carbonate (DMC) to produce fatty acid methyl ester (FAME) over synthesized Ca-La-Al mixed-oxide catalyst. The influence of different parameters on transesterification of Jatropha oil was investigated in a batch reactor. These parameters included reaction temperature (110-160 degrees C), reaction time (30-240 min), DM-to-oil molar ratio (4:1-18:1) and catalyst loading amount (1-10 wt.%, based on the oil weight). The mixed-oxide catalyst with a molar ratio of 6:2:1 (Ca-La-Al) showed high catalytic activity for FAME synthesis. More than 90% of FAME was obtained under the following reaction conditions: 150 degrees C, reaction temperature; 180 min, reaction time; 15:1, DMC-to-oil molar ratio; and 7 wt.% amount of catalyst loading. The catalyst also exhibited high stability and could be reused for up to five cycles with less than 5% yield reduction per cycle. (C) 2015 Elsevier Ltd. All rights reserved.