Active pipe-embedded building envelope is a new kind of external building wall or roof which usually has pipes embedded in it to let water circulate in these pipes for heat transfer. This structure may effectively intercept the heat/coolth from the ambient environment to indoor space and provide extra space conditioning for the indoor space. Frequency-domain finite-difference (FDFD) model can predict the frequency thermal response of active pipe-embedded building envelope directly and provide some important guidelines for system control and system sizing. This paper presents the experimental validation of this model in time domain by using Fourier series analysis. An experiment test rig was developed for the thermal response measurements of the pipe-embedded building envelope under pre-defined conditions. First, the measured time series of surface temperatures are transformed into complex Fourier series by using Discrete Fourier Transform and applied into the FDFD model as the boundary condition for calculation. Then, the calculated frequency thermal responses by FDFD model can be easily transformed into time series by using Inverse Discrete Fourier Transform. Finally, the time-domain thermal responses of FDFD model are obtained. The results show that the calculated time-domain thermal responses of the active pipe-embedded building envelope by using FDFD model agree well with the experimental measurements. (C) 2015 Elsevier B.V. All rights reserved.