In this work, a sensitive electrochemical method for the detection of H2O2 was proposed based on Fenton-type reaction on the electrode surface. A glassy carbon electrode modified with poly(azure A) (PAA), chitosan (CS) and copper ions, displaying a good electrochemical activity, was fabricated by cyclic voltammetry and the adsorption of Cu2+. Scanning electron microscopy-Energy dispersive spectroscopy analysis, infrared and Raman spectral characterization and XPS measurement showed the stable complexation of Cu2+ with the PAA-CS film. Hydroxyl radicals derived from the Fenton-type reaction between Cu2+ and H2O2 could effectively oxidize poly(azure A), leading to the great reduction-current change of the dye polymer in the electrode process. Under the optimized conditions, the fabricated electrode displayed a linear response in the H2O2 concentration range from 0.002 to 0.5 mM and that from 2.56 to 25.0 mM with a detection limit of 0.7 mM estimated at a signal-to-noise ratio of 3. The good analytical performance including low detection limit, fast response time, low cost, good anti-interference performance, satisfying stability, acceptable repeatability and reliable reproducibility were found from the proposed amperometric sensor, suggesting that the current work could provide a feasible approach for the non-enzymatic H2O2 detection. (C) 2015 Elsevier Ltd. All rights reserved.