A simple and time-saving analytical method for the determination of methylmercury in biological samples

Ji Hee Shin; Matthew J. Lee; Yujin Eom; Tai Gyu Lee

Journal of Industrial and Engineering Chemistry, Vol.35, 199-204, March, 2016

DOI10.1016/j.jiec.2015.12.032 Export Citation

A simple and time-saving analytical method for the determination of methylmercury in biological samples

Ji Hee Shin¹, Matthew J. Lee^{1, 2}, Yujin Eom¹, and Tai Gyu Lee^{1, 3, †}

¹Department of Chemical and Biomolecular Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea
²Tenafly High School, 19 Columbus Drive, Tenafly, NJ 07670, USA
³Department of Earth and Environmental Engineering, Columbia University, 500W. 120th Street, New York, NY 10027, USA

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In this study, a new method utilizing a sodium compound (either NaCl or Na2CO3) and acetonitrile (MeCN) was developed. The proposed method was validated by comparing the MeHg recoveries (%) of both of the certified reference materials and the market-purchased fish samples to the MeHg concentration obtained using AOAC Official Method 988.11 and the KFSC Method. The experimental results indicate that the newly proposed method in this work is a promising alternative, for its significantly simpler and faster sample pretreatment procedure with a MeHg recovery as high as those of AOAC Official Method 988.11 and the KFSC Method.

Keywords:Methylmercury;Biological sample;GC-ECD;AOAC official method 988.11;KFSC method

[References]

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Boening DW, Chemosphere, 40, 1335 (2000)
Huggett DB, Steevens JA, Allgood JC, Lutken CB, Grace CA, Benson WH, Chemosphere, 42, 923 (2001)
Jewett SC, Zhang X, Naidu AS, Kelley JJ, Dasher D, Duffy LK, Chemosphere, 50, 383 (2003)
Chien LC, Yeh CY, Jiang CB, Hsu CS, Han BC, Chemosphere, 67, 29 (2007)
Reyes LH, Rahman GMM, Kingston HMS, Anal. Chim. Acta, 631, 121 (2009)
Marusczak N, Larose C, Dommergue A, Paquet S, Beaulne JS, Maury-Brachet R, Lucotte M, Nedjai R, Ferrari CP, Sci. Total Environ., 409, 1909 (2011)
Shao D, Liang P, Kang Y, Wang H, Cheng Z, Wu S, Shi J, Lo SCL, Wang W, Wong MH, Chemosphere, 83, 443 (2011)
Spada L, Annicchiarico C, Cardellicchio N, Giandomenico S, Leo AD, Int. J. Hydrog. Environ. Health, 215, 418 (2012)
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Carrasco L, Barata C, Garcıa-Berthou E, Tobias A, Bayona JM, Dıez S, Chemosphere, 84, 1642 (2011)
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[1] Morita M, Yoshinaga J, Edmonds JS, Pure Appl. Chem., 70, 1585 (1998)

[2] Boening DW, Chemosphere, 40, 1335 (2000)

[3] Huggett DB, Steevens JA, Allgood JC, Lutken CB, Grace CA, Benson WH, Chemosphere, 42, 923 (2001)

[4] Jewett SC, Zhang X, Naidu AS, Kelley JJ, Dasher D, Duffy LK, Chemosphere, 50, 383 (2003)

[5] Chien LC, Yeh CY, Jiang CB, Hsu CS, Han BC, Chemosphere, 67, 29 (2007)

[6] Reyes LH, Rahman GMM, Kingston HMS, Anal. Chim. Acta, 631, 121 (2009)

[7] Marusczak N, Larose C, Dommergue A, Paquet S, Beaulne JS, Maury-Brachet R, Lucotte M, Nedjai R, Ferrari CP, Sci. Total Environ., 409, 1909 (2011)

[8] Shao D, Liang P, Kang Y, Wang H, Cheng Z, Wu S, Shi J, Lo SCL, Wang W, Wong MH, Chemosphere, 83, 443 (2011)

[9] Spada L, Annicchiarico C, Cardellicchio N, Giandomenico S, Leo AD, Int. J. Hydrog. Environ. Health, 215, 418 (2012)

[10] CAC. (Codex Alimentarius Commission)/GL 7-1991, Guideline Levels for Methyl Mercury in Fish, FAO (Food and Agriculture Organization), Rome, Italy, 1991.

[11] CREC (Commission Regulation of European Communities), Off. J. Eur. Communities (2006), L364, No 1881.

[12] CPG (Compliance Policy Guides) Sec 540.600, Fish, Shellfish, Crustaceans and Other Aquatic Animals-Fresh, Frozen or Processed-Methyl Mercury, US, FDA, Maryland, USA, 2007.

[13] Ruelas-Inzunza J, Hernandez-Osuna J, Paez-Osuna F, Chemosphere, 76, 415 (2009)

[14] Carrasco L, Barata C, Garcıa-Berthou E, Tobias A, Bayona JM, Dıez S, Chemosphere, 84, 1642 (2011)

[15] Kim CK, Lee TW, Lee KT, Lee JH, Lee CB, Chemosphere, 89, 1360 (2012)

[16] Lee KJ, Lee TG, J. Hazard. Mater., 241-242, 1 (2012)

[17] Won JH, Lee TG, Atmos. Environ., 62, 265 (2012)

[18] Cho JH, Eom Y, Jeon SH, Lee TG, J. Ind. Eng. Chem., 19(1), 144 (2013)

[19] Shin JH, Yonsei University, Republic of Korea, 2012 (M.S. thesis).

[20] AOAC (Association of Official Analytical Chemists) International, AOAC Official Method 988.11 Mercury (Methyl) in Fish and Shellfish, AOAC (Association of Official Analytical Chemists) International, Maryland, USA, 1992.

[21] KFDA (Korean Food and Drug Administration), Korean Food Standards Codex Volume I, 10-6-15-16, KFDA (Korean Food and Drug Administration), Seoul, Korea, 2012.

[22] Gomez-Ariza JL, Lorenzo F, Garcıa-Barrera T, Sanchez-Rodas D, Anal. Chim. Acta, 511, 165 (2004)

[23] Landaluze JS, de Diego A, Raposo JC, Madariaga JM, Anal. Chim. Acta, 508, 107 (2004)

[24] Nevado JJB, Martın-Doimeadios RCRM, Bernardo FJG, Moreno MJ, J. Chromatogr. A, 1093, 21 (2012)

[25] Marsalek P, Svobodova Z, Czech J. Food Sci., 24, 138 (2006)

[26] Abranko L, Kmellar B, Fodor P, Microchem J., 85, 122 (2007)

[27] Hajeb P, Jinap S, Bakar F, Bakar J, Food Addit. Contam., 26, 829 (2009)

[28] Kuballa T, Leonhardt E, Schoeberl K, Lachenmeier DW, Eur. Food Res. Technol., 228, 425 (2009)

[29] Chung SW, Chan BT, J. Chromatogr. A, 1218, 1260 (2011)

[30] Voegborlo RB, Matsuyama A, Adimado AA, Akagi H, Food Chem., 124, 1244 (2011)

[31] Gao Y, Shi Z, Long Z, Wu P, Zheng C, Hou X, Microchem J., 103, 1 (2012)

[32] Westoo G, Acta Chem. Scand., 21, 1790 (1967)

[33] Gerth WA, Hemmingsen EA, J. Comp. Physiol., 146, 129 (1982)

[34] Zhang J, Wu H, Kim E, El-Shourbagy TA, Biomed. Chromatogr., 23, 419 (2009)

[35] Zarate N, Araujo AN, Montenegro MCBSM, Perez-Olmos R, Am. J. Anal. Chem., 2, 491 (2011)